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Posted: Thu 2:51, 03 Mar 2011
Post subject: Rosetta Stone version 3 Nanotechnology in biomedic
Nanotechnology in biomedical applications development
Function on the basis of self-assembled membrane system; able to control the dose in a certain role of reactive oxygen species in apoptosis of cells mainly in the form of death and the discovery of apoptosis dependent on dose; found in lung adenocarcinoma cells (A549) and withered necrotic death of different secreted proteins, for future studies in greater depth the mechanism of apoptosis, and ultimately control of the target cells has laid a good foundation. Nano-materials-based sensors and molecular immunology research,
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, Fude Gang, Yao-Chun Shen Professor colloidal nanoparticles in super-Rayleigh scattering experiments found that nano-materials with strong nonlinear optical coefficient, and an antibody protein colloidal gold composite system has a strong super-Rayleigh scattering signal, which is expected to develop immune-related molecules can be integrated sensor and immune sensing and analysis devices. As a reliable,
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, accurate, low-cost means of detection, bio-sensors to obtain a wide range of applications. In particular, the biologically active molecules fixed on the electrode surface has become an important part of them. Given the limitations of the past, a variety of fixation methods, Chun-Wei Yuan of composite nanoparticles into polypyrrole tube and used for the construction of biosensors. High density of microtubules were arranged in film, hundreds of nanometer diameter, and the porous wall. It encapsulates a large number of enzymes, substrates and products to reduce the spread of disorder. The enzyme electrode showed good electrochemical performance. Professor Wang Xuemei, who conducted some of the supramolecular interaction with the DNA molecule and the recognition mode of approach, using some common dye molecules and some anti-tumor drugs interact with DNA, while a number of nanoparticle materials with liquid-solid interfacial compound with single,
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, double-stranded DNA molecules to study the role, can improve the sensitivity of correlation detection. Dr. Zhang Yu, who prepared a series of composite materials, nano-sterilization, ~ DAg / ZnO, Ag/TiO2, As / Si, etc., and have successfully prepared a number of features such as broad-spectrum sterilization of medical dressings. Lina, Chang Zhou Kai, who prepared a series of the thickness of the outer cover of the shell structure of nano materials, in some band absorbing properties with high efficiency, in electromagnetic compatibility of medical devices and electromagnetic protection and other aspects of human obvious application. As nano HAp with natural sources of convenience, low prices and good biological compatibility and many other advantages, Professor Lv Xiaoying, who has successfully prepared the natural hydroxyapatite nano-scale materials,
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, its physical and chemical properties were characterized and are being further medical application of technology. In carrying out the nano-optical control of drug release and the study of technology, we are the last nano liposome nano-technology based on the use of lipid microencapsulated drug release to the average effect of the drug, and attempts to improve the targeting of drugs ; Professor Li Xinsong and others controlled by self-assembly structure of the polymer to obtain nanostructured materials, combined with the package has taken shape in insulin release insulin nanoparticles technology; Professor Zhang Haiqian and others are using even helium properties of benzene photoisomerization will access an azobenzene bradykinin can be achieved using light of the purpose of controlled release drugs. Zheng Jie, Professor Zhang Dongsheng, who first discovered human fibroblasts and fibroblasts of the keratinocyte growth factor (KGF) can induce the HPV immortalized human cervical epithelial cell growth in soft agar; discovery of HPV immortalized human KGF cervical epithelial cells from the virus early gene transcription inhibition, but may stimulate the HPV immortalized human cervical epithelial cell urokinase-type plasminogen activator (uPA) secretion; They also found that arsenic trioxide can selectively inhibit the first $ ~ JHPV immortalized human cervical epithelial cells oncogenic viral protein expression, and induce the apoptosis, suggesting that treatment with arsenic trioxide HPV infection in vivo potential application of the tumor. We are currently carried out jointly with the magnetic core, and the outsourcing of metal oxide nano-materials in a number of cancer therapy applied technology research. VI Conclusion more nanotechnology applications in the biomedical research and development made a rough introduction. Acceleration of the development of large, involves the application of very broad and therefore only a very small list of some situations, especially in nano-technology in observing nano-structure and function of biological materials, such as single molecule detection of biological progress of very large current , there is no space for in this comprehensive introduction. Thanks: would like to thank the National Natural Science Fund, Ministry of Education, Teaching and Research Award Fund for young teachers and key teachers Fund, Natural Science Foundation of Jiangsu Province,
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, Jiangsu Province, Jiangsu Province Planning Commission, high-tech projects and research projects related to the support of our work; bad heart thanks university nanotechnology research centers, especially biomedical faculty, graduate student research efforts and hard work continue to make progress. I Huan} ∞
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